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2018-0402-01
Frontier Manufacturing Technology
posted:2018/04/26

視知覚の数理科学とその産業応用、特に各種画像処理技術、錯視、商用アートへの展開.

ARAI, Hitoshi Professor (Faculty of Education and Integrated Arts and Sciences)
collaborative researchers:新井 しのぶ
新井研究室では、人の視覚系が行っている脳内の情報処理を最先端の数学を使って研究し、更に画像処理、錯視(目の錯覚)、商用アートへの応用を行っています。また人の視覚を超えた超視覚システムの研究もしています。これまでに次のような発明をして、複数の特許を取得した。本研究の展開と産業応...
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2013-1022-03
Life sciences
posted:2013/10/25

生体内常在性物質による抗がん作用

NAMIKI, Hideo Professor (Faculty of Education and Integrated Arts and Sciences) (retired)
collaborative researchers:KIKUTA, Toshiteru Assistant Professor (retired)
・がん細胞に対して選択的に死滅・増殖抑制させる化合物Xを発見した・化合物Xは生体内に常在する物質であるため副作用がない
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2023-1025-03
Life sciences
posted:2023/10/25

株式会社BioPhenoMA 早稲田大学から新規ベンチャーがスタート!

ITO, Etsuro Professor (Faculty of Education and Integrated Arts and Sciences School of Education)
◆ 質量分析法などに比べて、圧倒的に簡便で迅速。前処理はほぼ不要。低価格も実現。◆ PCRによる核酸検出(NAAT)法と比べて、死菌・生菌などの区別が容易。◆ 創薬開発の効率化・個別化医療のほか、作用機序の解明により、新たな創薬・治療ターゲットの創出や、生物医学分野の更なる進歩に貢献。
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2023-1025-02
Life sciences
posted:2023/10/25

タンパク質の極微量定量法の検査への応用

ITO, Etsuro Professor (Faculty of Education and Integrated Arts and Sciences School of Education)
◆ タンパク質を検出するシグナルを増幅すれば極微量のタンパク質も定量できる。◆ サンドイッチELISA法とthioNADサイクリング法とを組み合わた 「酵素サイクリング改良法」を用いると極微量のタンパク質も定量できる。
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2022-1020-05
Life sciences
posted:2022/10/24

Sins of anticancer drugs

ITO, Etsuro Professor (Faculty of Education and Integrated Arts and Sciences School of Education)
● Whereas anyone can measure nucleic acids, what we really would like to know are the trace amounts of proteins that function in the body. ● Application of an ultrasensitive ELISA enables us to detect proteins responsible for malignant transformation.
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2021-0921-01
Life sciences
posted:2021/10/08

Activity change in the brain associated with pain relief

ITO, Etsuro Professor (Faculty of Education and Integrated Arts and Sciences School of Education)
● The oxyhemoglobin levels of lDLPFC became down, i.e., the activity was suppressed, during pain relief.
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2020-1012-01
Life sciences
posted:2020/10/27

Ultrasensitive antigen test for COVID-19

ITO, Etsuro Professor (Faculty of Education and Integrated Arts and Sciences School of Education)
● We propose a de novo antigen test for diagnosing COVID-19 using the combination of sandwich ELISA and thio-NAD cycling. Our test takes advantage of the spike (S1) proteins specific to the SARS-CoV-2 virus. 
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2019-1021-01
Life sciences
posted:2019/10/21

Development of new diagnosis using ultrasensitive ELISA

ITO, Etsuro Professor (Faculty of Education and Integrated Arts and Sciences School of Education)
● For this purpose, we have developed a de novo method using a sandwich ELISA combined with thio-NAD cycling.
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2016-1024-07
Life sciences
posted:2016/10/24

New Therapy of Precocious Puberty and Reproductive Dysfunction by Means of GnIH, a Novel Neurohormone

TSUTSUI, Kazuyoshi Professor (Faculty of Education and Integrated Arts and Sciences School of Education) (retired)
● Discovery of a novel neuro hormone(GnIH) (Fig.1)● Elucidation of the molecular mechanism of the GnIH/GNIH action to control the reproductive function  - Central precocious puberty (CPP) that GnIH/GNIH functional decline leads (Fig.2)  - Central reproductive dysfunction (CR...
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2012-0614-01
Environment
posted:2014/05/21

Environmentally-conscious product and waste product business management

NAGASAWA, Shinya Professor (Faculty of Commerce Graduate School of Commerce)
This project proposes methodology to scientifically develop market analysis and product management methods for environmentally-conscious products, as well as the creation of new waste product processing businesses. 
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2378
Frontier Nanotechnology / Materials
posted:2022/07/11
特願2022-73083

画像処理方法、画像処理装置、X線回折装置およびプログラム

ASAHI, Toru Professor (Faculty of Science and Engineering)
本シーズは、データ分析で用いられる密度ベースクラスタリングを応用した画像処理技術に関します。本シーズによれば、平面画像を構成する各画素に対応する位置に各画素の画素値に応じた密度で点を配置し、それらの点に密度に基づくクラスタリングを実行することで、所望の画素値を有する画素が密に...
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2020-1012-07
Life sciences
posted:2020/10/27

A Method for Chromatic Adaptation Conversion in Skin Disease Diagnosis

SOTA, Takayuki Professor (Faculty of Science and Engineering)
● Renunciation of perfect color reproduction  ● Custom setting of reference chromaticity coordinates● Realization of stable white balance
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2020-1012-06
Life sciences
posted:2020/10/27

Development of novel therapeutic strategy that targets pancreatic β cells for diabetes mellitus

GODA, Nobuhito Professor (Faculty of Science and Engineering)
● Increase in numbers of functional pancreatic β cells ● Creation of pancreatic β-like cells by transdifferentiation
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2019-1021-08
Life sciences
posted:2019/10/21

Method for monitoring the treatment effect of Myeloproliferative neoplasms

TSUNEDA, Satoshi Professor (Faculty of Science and Engineering)
● Usage of the fluorescence-dye-labeled probe exhibiting fluorescent intensity as a  function of the amount of V617F allele● JAK2 V617F allele burden can be quantified equivalent to the results by next- generation sequencing (NGS)● Available for the monitoring of slight i...
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2019-1021-06
Life sciences
posted:2019/10/21

Ultra-sensitive and high-performance biomolecule detection method

SOU, Keitaro Senior Researcher (Faculty of Science and Engineering)
collaborative researchers:Runkai Hu , TAKEOKA, Shinji Professor
● Conversion of detection principle from analog method to digital method.● Development of ultra-sensitive detection probes capable of single molecule detection.● Practical application of quantitative technology based on high-speed single molecule digital counting.
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2019-1021-03
Life sciences
posted:2019/10/21

Probes for theranostics that target denatured collagen

KOIDE, Takaki Professor (Faculty of Science and Engineering)
● Remarkable improvement of affinity to target by cyclization of CMPs● Optimization of cyclic CMP (cCMP) design using structure-activity relationship
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2018-1123-07
Life sciences
posted:2018/11/29

Natural compounds affecting cell differentiation

NAKAO, Yoichi Professor (Faculty of Science and Engineering)
●  In vitro neural differentiation model using embryonic stem cell●  Search for active compounds from marine organisms and foods
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1907
Life sciences
posted:2018/11/13
特許第6883845号

アストロサイト分化促進用組成物

NAKAO, Yoichi Professor (Faculty of Science and Engineering)
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1903
Life sciences
posted:2018/10/08
特許第6917050号

最適特性を有する非天然型タンパク質の製造方法

KIGA, Daisuke Professor (Faculty of Science and Engineering)
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2018-0927-03
Life sciences
posted:2018/09/27

Directed evolution of proteins by using novel engineering of genetic codes

KIGA, Daisuke Professor (Faculty of Science and Engineering)
● Our directed evolution creates a protein which  has only one modification site.● The key for the above evolution is our “simplified genetic codes” which do not  encode Lysine. ● Our ”moving average genetic code” keeps increasing of a desired property of proteins&nb...
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