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2319
Life sciences
Nanotechnology / Materials
posted：2020/04/14
複合ナノチューブを介した細胞内物質導入および抽出技術
MIYAKE, Takeo Associate Professor (Faculty of Science and Engineering Graduate School of Information, Production, and Systems)
2062
Life sciences
posted：2020/04/14
特願2018-158059
特願2018-158059 生体外で創る血管病モデルと薬剤スクリーニングへの応用
YAGI, Takanobu Researcher (Faculty of Science and Engineering Waseda Research Institute for Science and Engineering)
患者の血管病の病態に近似し、簡便かつ短期間で作製 可能で、血管組織が正常から病態へと経時間的に変化す るプロセスを解明することが可能な、ex vivoの疾患モ デルの作製方法を確立し、血管病の予防又は治療のため の薬剤のスクリーニングに利用可能な疾患モデルを提供 することを課題とする。
2065
Life sciences
posted：2020/02/10
特開2019-210254
特開2019-210254 植物のカゼインキナーゼ１（CK1)に対する阻害剤
YAMAGUCHI, Junichiro Professor (Faculty of Science and Engineering School of Advanced Science and Engineering)
2298
Information Communication
Life sciences
posted：2020/02/10
心電計の信号を分析して、特定疾患のリスク評価
IWASAKI, Kiyotaka Professor (Faculty of Science and Engineering Graduate School of Advanced Science and Engineering Cooperative Major in Advanced Biomedical Sciences)
2019-1021-07
Life sciences
posted：2019/10/21
Development of cosmetic products targeting cell endogenous activation
HARA, Taichi Professor (Faculty of Human Sciences)
● Degradation of abnormal proteins by enhancing autophagy.● Elimination of damaged mitochondria by mitophagy reduces the source of active oxygen.● Intrinsic protection from aging or environmental stress by increasing cellular stress response system
2019-1021-08
Life sciences
posted：2019/10/21
Method for monitoring the treatment effect of Myeloproliferative neoplasms
TSUNEDA, Satoshi Professor (Faculty of Science and Engineering)
● Usage of the fluorescence-dye-labeled probe exhibiting fluorescent intensity as a function of the amount of V617F allele● JAK2 V617F allele burden can be quantified equivalent to the results by next- generation sequencing (NGS)● Available for the monitoring of slight i...
2019-1021-06
Life sciences
posted：2019/10/21
Ultra-sensitive and high-performance biomolecule detection method
SOU, Keitaro Guest Researcher (Faculty of Science and Engineering)
collaborative researchers：Runkai Hu , TAKEOKA, Shinji Professor
● Conversion of detection principle from analog method to digital method.● Development of ultra-sensitive detection probes capable of single molecule detection.● Practical application of quantitative technology based on high-speed single molecule digital counting.
2019-1021-05
Life sciences
posted：2019/10/21
Regulation of Epithelial cell-cell communication to attenuate the rejection of suboptimal cell
MARUYAMA, Takeshi Assistant Professor (Affiliated organization)
● Optimal cells eliminate suboptimal cells● The mechanism similar to recognition of antigen presentaiton● Inhibition of ECA1/ECAR interaction suppresses the elimaination of suboptimal cells
2019-1021-04
Life sciences
posted：2019/10/21
Epithelial cell-cell communication to facilitate the aberrant cell elimination
MARUYAMA, Takeshi Assistant Professor (Affiliated organization)
● Epithelial cells eliminate precancerous cells● The mechanism similar to the recognition of antigen presentation● ECAR-targeting treatment enhance the elimination
2019-1021-03
Life sciences
posted：2019/10/21
Probes for theranostics that target denatured collagen
KOIDE, Takaki Professor (Faculty of Science and Engineering)
● Remarkable improvement of affinity to target by cyclization of CMPs● Optimization of cyclic CMP (cCMP) design using structure-activity relationship
2019-1021-02
Life sciences
posted：2019/10/21
Evaluation and identification of calorie restriction mimetic molecules
CHIBA, Takuya Professor (Faculty of Human Sciences)
● We developed the screening system for the identification of calorie restriction mimetics.● This system is unique, rapid and easy to use. ● This system is applicable both in vitro and in vivo.
2019-1021-01
Life sciences
posted：2019/10/21
Development of new diagnosis using ultrasensitive ELISA
ITO, Etsuro Professor (Faculty of Education and Integrated Arts and Sciences)
● For this purpose, we have developed a de novo method using a sandwich ELISA combined with thio-NAD cycling.
2130
Life sciences
posted：2019/07/30
特開2019-94494
特開2019-94494 重合体、樹脂組成物、防汚塗料組成物、重合体の製造方法、塗膜の表面にカルバメートを安定化する構造を生成する方法、塗膜の表面にカルバメートを安定化する構造を再生する方法
SUGA, Takeo Assistant Professor (Faculty of Science and Engineering School of Advanced Science and Engineering)
発明は、重合体、樹脂組成物、防汚塗料組成物、重合体の製造方法、塗膜の表面にカルバメートを安定化する構造を生成する方法、塗膜の表面にカルバメートを安定化する構造を再生する方法に関する。
2053
Life sciences
posted：2019/04/19
チキソトロピー性を有するゲルを用いる多層3次元細胞培養足場システム
TAKEDA, Naoya Professor (Faculty of Science and Engineering School of Advanced Science and Engineering)
1983
Life sciences
posted：2019/01/15
2018-200458
2018-200458 Cyto-cell chamber - High Cost Performance Re-usable Dish for Glass-bottom Observation
INOUE, Takafumi Professor (Faculty of Science and Engineering)
● Multi samples + Glass bottom dishes = High cost● Using reusable dishes● Adopted round cover glass for cell seeding port.
2018-1123-09
Life sciences
posted：2018/11/30
Ear thermometer for heat illness prevention
NAGASHIMA, Kei Professor (Faculty of Human Sciences)
● Health risks associated with hot climate during labor and sports are increasing. ● However, there are no effective bio-sensing devices to predict or judge such personal risk. ● We need to develop an accurate and simple device evaluating deep body temp...
2018-1123-08
Life sciences
posted：2018/11/30
A method of isolating reporter cells by a highly sensitive trap vector system
SEMBA, Kentaro Professor (Faculty of Science and Engineering School of Advanced Science and Engineering)
collaborative researchers：小林 雄太 , 若林 佑太郎
● To highly express the fluorescent reporter protein in isolation, GAL4-UAS system was employed.
2018-1123-07
Life sciences
posted：2018/11/29
Natural compounds affecting cell differentiation
NAKAO, Youichi Professor (Faculty of Science and Engineering)
● In vitro neural differentiation model using embryonic stem cell● Search for active compounds from marine organisms and foods
2018-1123-06
Life sciences
posted：2018/11/29
Chemo-enzymatic amide synthesis
KINO, Kuniki Professor (Faculty of Science and Engineering School of Advanced Science and Engineering Department of Applied Chemistry)
● A novel chemo-enzymatic reaction for the amide synthesis. ❍ Enzymatic reaction: activation of the carboxyl group of the substrate. ❍ Chemical reaction: nucleophilic substitution reaction to be various amides.
2018-1123-05
Life sciences
posted：2018/11/29
Biological Implant Material with Bone Seeking
MIZUNO, Jun Senior Researcher
collaborative researchers：塩澤 茉由子 , KUWAE, Hiroyuki Assistant Professor , SHOJI, Shuichi Professor
● Control surface morphology of implant in nanoscale. ● Combination of large and small nanostructures which has different functionalities, respectively.● Nanostructure formation process applicable for curved surfaces.
