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2021-0921-07
Life sciences
posted:2021/10/08

Wireless monitoring system for human small signal detection

MIYAKE, Takeo Professor (Faculty of Science and Engineering Graduate School of Information, Production, and Systems)
●  New principle: the parity-time symmetric resonator circuits●  Add a negative resistance to the detection circuit only●  Wireless monitoring of resistance, inductance, and capacitance change 
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2021-0921-06
Life sciences
posted:2021/10/08

Molecule delivering nanotube stamp and stamping system

MIYAKE, Takeo Professor (Faculty of Science and Engineering Graduate School of Information, Production, and Systems)
●  Delivering substances with different sizes, shapes, and charges into cells  ●  We have developed a hybrid nanotube (NT) stamp and its stamping system.  ● The proposed technology can be used for basic and applied research (regenerative medicine,...
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2021-0921-05
Life sciences
posted:2021/10/08

Monitor for stress substances

OHASHI, Keishi Senior Researcher (Research Council (Research Organization) Institute for Nanoscience & Nanotechnology)
● Development of compact, easy-to-handle, fast-response silicon transistor sensor (Fig.2)● Simultaneous detection and multifaceted understanding of markers of different origins● Simple detection from minute amounts of saliva and sweat
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2021-0921-04
Life sciences
posted:2021/10/08

Modulation of Brain Activity by tDCS Effects on Human Decision Making

HIRAYAMA, Kento Research Associate (Faculty of Human Sciences School of Human Sciences)
collaborative researchers:OSU, Rieko Professor
● Transcranial direct current electrical stimulation (tDCS) (Figure 1) can increase or decrease neural activity continuously for several hours. ● The activity of the posterior parietal cortex was changed by tDCS during the task of measuring the frequency of choice for eac...
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2021-0921-03
Life sciences
posted:2021/10/08

Epithelial cell-cell communication to attenuate the rejection of suboptimal cells

MARUYAMA, Takeshi Associate Professor (Affiliated organization Waseda Institute for Advanced Study)
collaborative researchers:鮎川 志優
● Optimal cells eliminate suboptimal cells● The mechanism of epithelial cell-cell  communication via the interaction between a ligand and a receptor● MHC-I-targeting treatment suppresses the elimination
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2021-0921-02
Life sciences
posted:2021/10/08

Epithelial cell-cell communication to facilitate the aberrant cell elimination

MARUYAMA, Takeshi Associate Professor (Affiliated organization Waseda Institute for Advanced Study)
● Epithelial cells eliminate precancerous cells● The mechanism of epithelial cell-cell  communication via the interaction between Ligand and  Receptor● AltR-targeting treatment enhances the elimination
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2021-0921-01
Life sciences
posted:2021/10/08

Activity change in the brain associated with pain relief

ITO, Etsuro Professor (Faculty of Education and Integrated Arts and Sciences School of Education)
● The oxyhemoglobin levels of lDLPFC became down, i.e., the activity was suppressed, during pain relief.
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2021-0921-09
Life sciences
posted:2021/10/08

In vitro NASH model with ballooned hepatocytes

SAKAGUCHI, Katsuhisa Associate Professor (Faculty of Science and Engineering Graduate School of Advanced Science and Engineering)
● When human fibroblasts and human hepatocytes are co-cultured, collected in sheets using UPCELL and     cultured in a high-glycolipid environment, ballooned hepatocytes are induced. 
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2021-0921-08
Life sciences
posted:2021/10/08

Research and development of functional ingredients to protect the liver from alcohol consumption

HARA, Taichi Professor (Faculty of Human Sciences School of Human Sciences)
● Identify functional materials that reduce alcohol-induced liver injury. ● Promotes the degradation of acetaldehyde in liver cells. ● Develop a highly concentrated hydrogen water generator that reduces the amount of intracellular acetaldehyde.
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2263
Life sciences
posted:2021/06/07
特開2021-81191

異種接合材の純モード  層間破壊靱性評価試験法の開発

HOSOI, Atsushi Professor (Faculty of Science and Engineering School of Fundamental Science and Engineering)
◆ DCB試験の応用 ◆ 異種材接合に伴う混合モードの影響を除去◆ 熱残留応力の影響をキャンセル◆ 正確なモードⅠ層間破壊靱性の評価  
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2354
Life sciences
posted:2021/01/12

光スイッチ

KITA, Tomohiro Associate Professor (Faculty of Science and Engineering School of Advanced Science and Engineering)
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2020-1012-07
Life sciences
posted:2020/10/27

A Method for Chromatic Adaptation Conversion in Skin Disease Diagnosis

SOTA, Takayuki Professor (Faculty of Science and Engineering)
● Renunciation of perfect color reproduction  ● Custom setting of reference chromaticity coordinates● Realization of stable white balance
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2020-1012-06
Life sciences
posted:2020/10/27

Development of novel therapeutic strategy that targets pancreatic β cells for diabetes mellitus

GODA, Nobuhito Professor (Faculty of Science and Engineering)
● Increase in numbers of functional pancreatic β cells ● Creation of pancreatic β-like cells by transdifferentiation
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2020-1012-05
Life sciences
posted:2020/10/27

High sensitivity DOI-PET detector

KATAOKA, Jun Professor (Faculty of Science and Engineering School of Advanced Science and Engineering Department of Applied Physics)
● Resolution improvement  for the PET scaner● 3D measurement of  incident gamma rays  ● Novel optical sensor of the magnetic field resistant
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2020-1012-04
Life sciences
posted:2020/10/27

Success in promoting plant growth for biodiesel

TOMINAGA, Motoki Associate Professor (Faculty of Education and Integrated Arts and Sciences)
● We Focused on Camelina its oil from seeds used as a raw material for biodiesel.● Succeeded in enhancement of seed production by heterologously expressing the high-speed  Chara-Arabidopsis chimeric myosin XI gene in Camerina
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2020-1012-01
Life sciences
posted:2020/10/27

Ultrasensitive antigen test for COVID-19

ITO, Etsuro Professor (Faculty of Education and Integrated Arts and Sciences School of Education)
● We propose a de novo antigen test for diagnosing COVID-19 using the combination of sandwich ELISA and thio-NAD cycling. Our test takes advantage of the spike (S1) proteins specific to the SARS-CoV-2 virus. 
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2062
Life sciences
posted:2020/04/14
特願2018-158059

生体外で創る血管病モデルと薬剤スクリーニングへの応用

YAGI, Takanobu Researcher (Faculty of Science and Engineering Waseda Research Institute for Science and Engineering)
患者の血管病の病態に近似し、簡便かつ短期間で作製 可能で、血管組織が正常から病態へと経時間的に変化す るプロセスを解明することが可能な、ex vivoの疾患モ デルの作製方法を確立し、血管病の予防又は治療のため の薬剤のスクリーニングに利用可能な疾患モデルを提供 することを課題とする。
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2298
Information Communication Life sciences
posted:2020/02/10
特開2021-112479

深層学習を用いた心電図からの大動脈弁狭窄症(AS)識別法

IWASAKI, Kiyotaka Professor (Faculty of Science and Engineering Graduate School of Advanced Science and Engineering Cooperative Major in Advanced Biomedical Sciences)
心電図データから1拍画像を生成し,その画像に対して深層学習によって,「AS」か「ASではない」かの2クラス分類を行う.ここで,ネットワークの学習のための訓練データのアノテーションには,心臓超音波映像から専門医が判断する.得られた学習機とGrad-CAMを用いて,「AS」あるいは「ASではない」...
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2019-1021-07
Life sciences
posted:2019/10/21

Development of cosmetic products targeting cell endogenous activation

HARA, Taichi Professor (Faculty of Human Sciences School of Human Sciences)
● Degradation of abnormal proteins by enhancing autophagy.● Elimination of damaged mitochondria by mitophagy reduces the source of active oxygen.● Intrinsic protection from aging or environmental stress by increasing cellular stress response system
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2019-1021-08
Life sciences
posted:2019/10/21

Method for monitoring the treatment effect of Myeloproliferative neoplasms

TSUNEDA, Satoshi Professor (Faculty of Science and Engineering)
● Usage of the fluorescence-dye-labeled probe exhibiting fluorescent intensity as a  function of the amount of V617F allele● JAK2 V617F allele burden can be quantified equivalent to the results by next- generation sequencing (NGS)● Available for the monitoring of slight i...
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