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2263
Life sciences
posted：2021/06/07
特開2021-81191
特開2021-81191 異種接合材の純モード 層間破壊靱性評価試験法の開発
HOSOI, Atsushi Professor (Faculty of Science and Engineering School of Fundamental Science and Engineering)
◆ DCB試験の応用 ◆ 異種材接合に伴う混合モードの影響を除去◆ 熱残留応力の影響をキャンセル◆ 正確なモードⅠ層間破壊靱性の評価
2020-1012-07
Life sciences
posted：2020/10/27
A Method for Chromatic Adaptation Conversion in Skin Disease Diagnosis
SOTA, Takayuki Professor (Faculty of Science and Engineering)
● Renunciation of perfect color reproduction ● Custom setting of reference chromaticity coordinates● Realization of stable white balance
2020-1012-06
Life sciences
posted：2020/10/27
Development of novel therapeutic strategy that targets pancreatic β cells for diabetes mellitus
GODA, Nobuhito Professor (Faculty of Science and Engineering)
● Increase in numbers of functional pancreatic β cells ● Creation of pancreatic β-like cells by transdifferentiation
2020-1012-05
Life sciences
posted：2020/10/27
High sensitivity DOI-PET detector
KATAOKA, Jun Professor (Faculty of Science and Engineering School of Advanced Science and Engineering Department of Applied Physics)
● Resolution improvement for the PET scaner● 3D measurement of incident gamma rays ● Novel optical sensor of the magnetic field resistant
2020-1012-04
Life sciences
posted：2020/10/27
Success in promoting plant growth for biodiesel
TOMINAGA, Motoki Associate Professor (Faculty of Education and Integrated Arts and Sciences)
● We Focused on Camelina its oil from seeds used as a raw material for biodiesel.● Succeeded in enhancement of seed production by heterologously expressing the high-speed Chara-Arabidopsis chimeric myosin XI gene in Camerina
2020-1012-01
Life sciences
posted：2020/10/27
Ultrasensitive antigen test for COVID-19
ITO, Etsuro Professor (Faculty of Education and Integrated Arts and Sciences)
● We propose a de novo antigen test for diagnosing COVID-19 using the combination of sandwich ELISA and thio-NAD cycling. Our test takes advantage of the spike (S1) proteins specific to the SARS-CoV-2 virus.
2020-1012-03
Life sciences
posted：2020/10/27
Regulation of Epithelial cell-cell communication to attenuate the rejection of suboptimal cell
MARUYAMA, Takeshi Associate Professor (Affiliated organization Waseda Institute for Advanced Study)
● Optimal cells eliminate suboptimal cells● The mechanism similar to recognition of antigen presentation● Inhibition of ECA1/ECAR interaction suppresses the elimination of suboptimal cells
2020-1012-02
Life sciences
posted：2020/10/27
Epithelial cell-cell communication to facilitate the aberrant cell elimination
MARUYAMA, Takeshi Associate Professor (Affiliated organization Waseda Institute for Advanced Study)
● Epithelial cells eliminate precancerous cells● The mechanism similar to the recognition of antigen presentation● ECAR-targeting treatment enhance the elimination
2062
Life sciences
posted：2020/04/14
特願2018-158059
特願2018-158059 生体外で創る血管病モデルと薬剤スクリーニングへの応用
YAGI, Takanobu Researcher (Faculty of Science and Engineering Waseda Research Institute for Science and Engineering)
患者の血管病の病態に近似し、簡便かつ短期間で作製 可能で、血管組織が正常から病態へと経時間的に変化す るプロセスを解明することが可能な、ex vivoの疾患モ デルの作製方法を確立し、血管病の予防又は治療のため の薬剤のスクリーニングに利用可能な疾患モデルを提供 することを課題とする。
2298
Information Communication
Life sciences
posted：2020/02/10
心電計の信号を分析して、特定疾患のリスク評価
IWASAKI, Kiyotaka Professor (Faculty of Science and Engineering Graduate School of Advanced Science and Engineering Cooperative Major in Advanced Biomedical Sciences)
2019-1021-07
Life sciences
posted：2019/10/21
Development of cosmetic products targeting cell endogenous activation
HARA, Taichi Professor (Faculty of Human Sciences)
● Degradation of abnormal proteins by enhancing autophagy.● Elimination of damaged mitochondria by mitophagy reduces the source of active oxygen.● Intrinsic protection from aging or environmental stress by increasing cellular stress response system
2019-1021-08
Life sciences
posted：2019/10/21
Method for monitoring the treatment effect of Myeloproliferative neoplasms
TSUNEDA, Satoshi Professor (Faculty of Science and Engineering)
● Usage of the fluorescence-dye-labeled probe exhibiting fluorescent intensity as a function of the amount of V617F allele● JAK2 V617F allele burden can be quantified equivalent to the results by next- generation sequencing (NGS)● Available for the monitoring of slight i...
2019-1021-06
Life sciences
posted：2019/10/21
Ultra-sensitive and high-performance biomolecule detection method
SOU, Keitaro Guest Researcher (Faculty of Science and Engineering)
collaborative researchers：Runkai Hu , TAKEOKA, Shinji Professor
● Conversion of detection principle from analog method to digital method.● Development of ultra-sensitive detection probes capable of single molecule detection.● Practical application of quantitative technology based on high-speed single molecule digital counting.
2019-1021-03
Life sciences
posted：2019/10/21
Probes for theranostics that target denatured collagen
KOIDE, Takaki Professor (Faculty of Science and Engineering)
● Remarkable improvement of affinity to target by cyclization of CMPs● Optimization of cyclic CMP (cCMP) design using structure-activity relationship
2019-1021-02
Life sciences
posted：2019/10/21
Evaluation and identification of calorie restriction mimetic molecules
CHIBA, Takuya Professor (Faculty of Human Sciences)
● We developed the screening system for the identification of calorie restriction mimetics.● This system is unique, rapid and easy to use. ● This system is applicable both in vitro and in vivo.
2019-1021-01
Life sciences
posted：2019/10/21
Development of new diagnosis using ultrasensitive ELISA
ITO, Etsuro Professor (Faculty of Education and Integrated Arts and Sciences)
● For this purpose, we have developed a de novo method using a sandwich ELISA combined with thio-NAD cycling.
2053
Life sciences
posted：2019/04/19
チキソトロピー性を有するゲルを用いる多層3次元細胞培養足場システム
TAKEDA, Naoya Professor (Faculty of Science and Engineering School of Advanced Science and Engineering)
1983
Life sciences
posted：2019/01/15
2018-200458
2018-200458 Cyto-cell chamber - High Cost Performance Re-usable Dish for Glass-bottom Observation
INOUE, Takafumi Professor (Faculty of Science and Engineering)
● Multi samples + Glass bottom dishes = High cost● Using reusable dishes● Adopted round cover glass for cell seeding port.
2018-1123-09
Life sciences
posted：2018/11/30
Ear thermometer for heat illness prevention
NAGASHIMA, Kei Professor (Faculty of Human Sciences)
● Health risks associated with hot climate during labor and sports are increasing. ● However, there are no effective bio-sensing devices to predict or judge such personal risk. ● We need to develop an accurate and simple device evaluating deep body temp...
