Epithelial cell-cell communication to facilitate or attenuate the aberrant cell elimination


●  Malignant/incurable cancer disease   
●  Cancer prevention to eliminate precancerous cells
●  Poor survival of  transplanted cells 
●  The cells are eliminated even upon the immunosuppressant


● Optimal cells eliminate suboptimal cells
● The mechanism of epithelial cell-cell  communication
      via the interaction between Ligand and  Receptor
● AltR-targeting treatment enhances or suppresses the elimination


● A novel mechanism to promote or suppress the elimination
    of suboptimal cells
● Low cell toxicity


● Carcinoma
● Cell transplantation
posted: 2022/10/24