Epithelial cell-cell communication to facilitate or attenuate the aberrant cell elimination

2022-1020-01
researcher's name
about researcher MARUYAMA, Takeshi Part-time Lecturer
affiliation
Affiliated organization Waseda Institute for Advanced Study
keyword

background

●  Malignant/incurable cancer disease   
●  Cancer prevention to eliminate precancerous cells
●  Poor survival of  transplanted cells 
●  The cells are eliminated even upon the immunosuppressant

summary

● Optimal cells eliminate suboptimal cells
● The mechanism of epithelial cell-cell  communication
      via the interaction between Ligand and  Receptor
● AltR-targeting treatment enhances or suppresses the elimination

predominance

● A novel mechanism to promote or suppress the elimination
    of suboptimal cells
● Low cell toxicity

application/development

● Carcinoma
● Cell transplantation

material

  • 丸山先生_上皮細胞相互作用による非免疫系を介した排除促進・抑制作用.pdf

same researcher's seeds

  • Epithelial cell-cell communication to facilitate the aberrant cell elimination
  • Epithelial cell-cell communication to attenuate the rejection of suboptimal cells
posted: 2022/10/24