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2023-1025-05
Life sciences
posted:2023/10/25

細胞老化の制御による創薬:NASH, HCC治療薬を例として

CHIBA, Takuya Professor (Faculty of Human Sciences School of Human Sciences)
◆スクリーニングの結果、非アルコール性脂肪性肝疾患/非アルコール性脂肪及び肝がんの予防・治療剤候補を同定した。
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2023-1025-04
Life sciences
posted:2023/10/25

新奇な環状ペプチド “ジケトピペラジン(DKP)”のスマートバイオプロセスによる機能性の開発研究

HARA, Taichi Professor (Faculty of Human Sciences School of Human Sciences)
collaborative researchers:YANO, Satoshi Assistant Professor
◆ 細胞内の品質管理を担うオートファジーを活性化することで、健康増進に寄与する可能性がある。◆ 開発研究によって、ある種のDKPに細胞内のオートファジーを活性化する作用を見出している。◆ オートファジーの活性化は、美容や妊活などにも機能することから、DKPの新奇の健康機能性を開拓できる。
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2022-1021-01
Life sciences
posted:2022/10/24

Screening and evaluation system for anti-aging chemicals

CHIBA, Takuya Professor (Faculty of Human Sciences School of Human Sciences)
● Screening system for anti-aging chemicals● Genes related to life extension and use thereof
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2022-1020-03
Life sciences
posted:2022/10/24

Research on improving mental health problems using the iACT self-help application "emol”

OTSUKI, Tomu Professor (Faculty of Human Sciences School of Human Sciences)
● Realize an intervention with iACT self-help  application.
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2535DIV
Life sciences
posted:2022/06/13
特開2022-68362

医療システム及びそれを実行する方法

KUMANO, Hiroaki Professor (Faculty of Human Sciences School of Human Sciences)
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2489
Life sciences
posted:2022/05/02
特開2022-42008

医療システム及びそれを実行する方法

KUMANO, Hiroaki Professor (Faculty of Human Sciences School of Human Sciences)
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2335
Life sciences
posted:2021/11/10
特開2021-168603

胚盤胞形成促進剤

HARA, Taichi Professor (Faculty of Human Sciences School of Human Sciences)
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2021-0921-08
Life sciences
posted:2021/10/08

Research and development of functional ingredients to protect the liver from alcohol consumption

HARA, Taichi Professor (Faculty of Human Sciences School of Human Sciences)
● Identify functional materials that reduce alcohol-induced liver injury. ● Promotes the degradation of acetaldehyde in liver cells. ● Develop a highly concentrated hydrogen water generator that reduces the amount of intracellular acetaldehyde.
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2019-1021-07
Life sciences
posted:2019/10/21

Development of cosmetic products targeting cell endogenous activation

HARA, Taichi Professor (Faculty of Human Sciences School of Human Sciences)
● Degradation of abnormal proteins by enhancing autophagy.● Elimination of damaged mitochondria by mitophagy reduces the source of active oxygen.● Intrinsic protection from aging or environmental stress by increasing cellular stress response system
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2019-1021-02
Life sciences
posted:2019/10/21

Evaluation and identification of calorie restriction mimetic molecules

CHIBA, Takuya Professor (Faculty of Human Sciences School of Human Sciences)
● We developed the screening system for the identification of calorie restriction mimetics.● This system is unique, rapid and easy to use. ● This system is applicable both in vitro and in vivo.
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2018-0927-04
Life sciences
posted:2018/09/27

Drug screening targeting intracellular accumulation of abnormal proteins

HARA, Taichi Professor (Faculty of Human Sciences School of Human Sciences)
● Elucidation of the molecular mechanisms for the intracellular accumulation of abnormal proteins (Fig. 2).  ● Development of screening technique targeting protein quality control systems.
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2013-0130-03
Life sciences
posted:2014/05/21

Technology for screening anti-aging substances

CHIBA, Takuya Professor (Faculty of Human Sciences School of Human Sciences)
We have established a system of using cultured cells for screening and transgenic mice to examine and evaluate substances that have the equivalent effect in anti-aging as calorie restriction. Pro-longevity transcription factor binding sites (DFCR-RE: dwarfism and calorie restr...
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2013-0130-04
Life sciences
posted:2014/05/21

Deficient DNA damage response and progeria

CHIBA, Takuya Professor (Faculty of Human Sciences School of Human Sciences)
Through the functional analysis of multiple proteins involved in the copying, repair and recombination of DNA identified as being the genetic cause of progeria, we are carrying out research into the breakdown and accelerated aging of the mechanism that maintains genomic homeos...
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2013-0130-15
Life sciences
posted:2014/05/21

Evaluation of comfort through measurement of brain activity

KUMANO, Hiroaki Professor (Faculty of Human Sciences School of Human Sciences)
By measuring blood flow in the brain in real time through optical topography (NIRS), we can provide an objective, numerical index of the state of comfort or emotions. This will assist in the search for more effective stimulatory conditions and designs.
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2013-0130-16
Life sciences
posted:2014/05/21

Ways to alleviate mood disorders through attention training

KUMANO, Hiroaki Professor (Faculty of Human Sciences School of Human Sciences)
Focusing on “rumination = repeated recalling of past events and being tormented by them,” often seen in depression, we are developing a form of neurobehavioral therapy based on attention training to alleviate rumination. We can provide treatments that suit the symptoms of the ...
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2013-0130-17
Life sciences
posted:2014/05/21

Interfaces that make use of the characteristics of cutaneous sensation

FUJIMOTO, Hiroshi Professor (Faculty of Human Sciences School of Human Sciences)
Designing an information communicating device for the visually impairedAnalyzing the characteristics of a variety of tactile sensing such as differences in the surface area, the layer structure and hardness (Young’s modulus), slipperiness, etc., and proposing devices that make...
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2013-0130-18
Life sciences
posted:2014/05/21

The development of facilities and equipment based on analyses of the motor functions of the legs

FUJIMOTO, Hiroshi Professor (Faculty of Human Sciences School of Human Sciences)
Analyzing the effects of tactile paving and inclined obstacles on the walking of healthy people, the elderly and injured people (an examination of stress or danger of tripping while walking).Elucidating the mechanical properties of the structure of the foot (e.g., the arch) wh...
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