Evaluation and identification of calorie restriction mimetic molecules

2019-1021-02
researcher's name
affiliation
research field
Environmental physiology (including physical medicine and nutritional physiology),Eating habits,General medical chemistry,Experimental pathology
keyword

background

● Clear scientific evidences are needed to claim functions.
● Rapid and simple evaluation systems for the screening of anti-aging chemicals are required.
● Calorie restriction (CR) is most reliable anti-aging intervention, but enforcing CR in humans are difficult.

summary

● We developed the screening system for the identification of calorie restriction mimetics.
● This system is unique, rapid and easy to use.
● This system is applicable both in vitro and in vivo.

predominance

● Applicable for new candidates discovery and evaluation of known candidates.
● Applicable for the large scale and the high-throughput screening.
● Predictable in a short time for biological action.

application/development

● Cosmetics
● Pharmaceuticals
● Foods

material

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posted: 2019/10/21