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2011-0517-02
Life sciences
posted:2014/05/21

Visualization of the brain’s response to stimuli (smell) in a murine model using noninvasive measuring of biomagnetism

ISHIYAMA, Atsushi Professor (Faculty of Science and Engineering School of Advanced Science and Engineering)
The SQUID (superconducting quantum interference device), which is a high sensitivity magnetic sensor, is able to measure subtle magnetic fields (magnetoencephalographs) created by nervous activity, and it is not hindered by the skull. This allows the accurate and individual tr...
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2011-0517-03
Life sciences
posted:2014/05/21

Comparison of a murine model with humans using noninvasive measuring of biomagnetism, and its application in heart disease diagnosis

ISHIYAMA, Atsushi Professor (Faculty of Science and Engineering School of Advanced Science and Engineering)
We can provide a method of early heart disease detection that combines life science techniques with SQUID* measurements.For example, we can create a murine model of myocardial infarction (a knockout mouse), and take magnetocardiographs using SQUID from birth until the onset of...
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2011-0517-04
Life sciences
posted:2014/05/21

Comparison of a murine model with humans using noninvasive measuring of biomagnetism, and its application in brain disease diagnosis

ISHIYAMA, Atsushi Professor (Faculty of Science and Engineering School of Advanced Science and Engineering)
SQUID (superconducting quantum interference device), which is a high sensitivity magnetic sensor, is able to measure weak magnetic fields (magnetoencephalographs) generated by neurotransmissions (brain activity) without being obstructed by the skull. For example, using SQUID t...
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2023-1025-03
Life sciences
posted:2023/10/25

株式会社BioPhenoMA 早稲田大学から新規ベンチャーがスタート!

ITO, Etsuro Professor (Faculty of Education and Integrated Arts and Sciences School of Education)
◆ 質量分析法などに比べて、圧倒的に簡便で迅速。前処理はほぼ不要。低価格も実現。◆ PCRによる核酸検出(NAAT)法と比べて、死菌・生菌などの区別が容易。◆ 創薬開発の効率化・個別化医療のほか、作用機序の解明により、新たな創薬・治療ターゲットの創出や、生物医学分野の更なる進歩に貢献。
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2023-1025-02
Life sciences
posted:2023/10/25

タンパク質の極微量定量法の検査への応用

ITO, Etsuro Professor (Faculty of Education and Integrated Arts and Sciences School of Education)
◆ タンパク質を検出するシグナルを増幅すれば極微量のタンパク質も定量できる。◆ サンドイッチELISA法とthioNADサイクリング法とを組み合わた 「酵素サイクリング改良法」を用いると極微量のタンパク質も定量できる。
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2022-1020-05
Life sciences
posted:2022/10/24

Sins of anticancer drugs

ITO, Etsuro Professor (Faculty of Education and Integrated Arts and Sciences School of Education)
● Whereas anyone can measure nucleic acids, what we really would like to know are the trace amounts of proteins that function in the body. ● Application of an ultrasensitive ELISA enables us to detect proteins responsible for malignant transformation.
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2021-0921-01
Life sciences
posted:2021/10/08

Activity change in the brain associated with pain relief

ITO, Etsuro Professor (Faculty of Education and Integrated Arts and Sciences School of Education)
● The oxyhemoglobin levels of lDLPFC became down, i.e., the activity was suppressed, during pain relief.
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2020-1012-01
Life sciences
posted:2020/10/27

Ultrasensitive antigen test for COVID-19

ITO, Etsuro Professor (Faculty of Education and Integrated Arts and Sciences School of Education)
● We propose a de novo antigen test for diagnosing COVID-19 using the combination of sandwich ELISA and thio-NAD cycling. Our test takes advantage of the spike (S1) proteins specific to the SARS-CoV-2 virus. 
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2019-1021-01
Life sciences
posted:2019/10/21

Development of new diagnosis using ultrasensitive ELISA

ITO, Etsuro Professor (Faculty of Education and Integrated Arts and Sciences School of Education)
● For this purpose, we have developed a de novo method using a sandwich ELISA combined with thio-NAD cycling.
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2457
Social Infrastructure
posted:2021/05/14

病変状態を模擬した心臓弁等の臓器モデルの作製

IWASAKI, Kiyotaka Professor (Faculty of Science and Engineering Graduate School of Advanced Science and Engineering Cooperative Major in Advanced Biomedical Sciences)
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2252
Social Infrastructure
posted:2019/12/11

心臓弁尖作製用機器で作成した弁、縫合ガイド、および、弁尖作製用機器

IWASAKI, Kiyotaka Professor (Faculty of Science and Engineering Graduate School of Advanced Science and Engineering Cooperative Major in Advanced Biomedical Sciences)
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1749
Social Infrastructure
posted:2015/11/05
第6590278号

血液濾過器の流れの可視化試験装置

IWASAKI, Kiyotaka Professor (Faculty of Science and Engineering Graduate School of Advanced Science and Engineering Cooperative Major in Advanced Biomedical Sciences)
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2011-0909-05
Life sciences Manufacturing Technology
posted:2014/05/21

A durability testing device for stents and a method of evaluation

IWASAKI, Kiyotaka Professor (Faculty of Science and Engineering Graduate School of Advanced Science and Engineering Cooperative Major in Advanced Biomedical Sciences)
We developed a testing device that could accurately simulate the stress environment of the area where the stent is inserted. The development of a system that takes into account the application of stress in the form of a combined twisting and stretching force, and the mechanica...
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2011-0909-06
Life sciences Manufacturing Technology
posted:2014/05/21

Acellularization of heart valves

IWASAKI, Kiyotaka Professor (Faculty of Science and Engineering Graduate School of Advanced Science and Engineering Cooperative Major in Advanced Biomedical Sciences)
One of the ways of prolonging the life of tissue valves is to not treat them chemically, and use acellular tissue from porcine heart valves. A unique method of microwave irradiation combined with a simulated in vivo environment (controlled surfactant flow and pressure through ...
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939
Life sciences
posted:2014/04/03

Simulated constricted blood vessel and manufacturing method thereof

IWASAKI, Kiyotaka Professor (Faculty of Science and Engineering Graduate School of Advanced Science and Engineering Cooperative Major in Advanced Biomedical Sciences)
This invention is an artificial blood vessel for modeling stenotic lesions caused by the calcification of blood vessels, and the manufacturing method thereof.Elasticity near to that of an actual human constricted blood vessel can be obtained by mixing calcium carbonate powder ...
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2023-0127-06
Nanotechnology / Materials
posted:2023/01/27

切り紙構造を用いたフレキシブル熱電発電デバイス

IWASE, Eiji Professor (Faculty of Science and Engineering School of Fundamental Science and Engineering)
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2451
Environment
posted:2021/12/07
特開2023- 51302

薄膜熱電発電デバイス、薄膜熱電発電デバイス部品及びその製造方法

IWASE, Eiji Professor (Faculty of Science and Engineering School of Fundamental Science and Engineering)
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2020-1124-03
Nanotechnology / Materials
posted:2020/12/17

Operation of 3-D MEMS micro mirror by single superposed driving signal

IWASE, Eiji Professor (Faculty of Science and Engineering School of Fundamental Science and Engineering)
● By single driving apparatus, MEMS micro mirror is actuated in  three resonant modes● MEMS micro mirror is operated in 3-D by single superposed signal with the three resonant frequencies
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2019-0312-06
Nanotechnology / Materials
posted:2019/04/22

Display Device for Visual Texture

IWASE, Eiji Professor (Faculty of Science and Engineering School of Fundamental Science and Engineering)
● We proposed spatial mixing using glossy and matte surfaces for reconstruction of visual texture.● Our method can display various visual texture by changing the area ratio of glossy and matte surfaces.
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2017-0223-04
Nanotechnology / Materials
posted:2017/02/23

Operation of 3-D MEMS Micro Mirror by Single Superposed Driving Signal

IWASE, Eiji Professor (Faculty of Science and Engineering School of Fundamental Science and Engineering)
● By single driving apparatus, MEMS micro mirror is actuated in  three resonant modes● MEMS micro mirror is operated in 3-D by single superposed signal with the three resonant frequencies  
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