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2018-1123-06
Life sciences
posted:2018/11/29

Chemo-enzymatic amide synthesis

KINO, Kuniki Professor (Faculty of Science and Engineering School of Advanced Science and Engineering Department of Applied Chemistry)
●  A novel chemo-enzymatic reaction for the amide synthesis. ❍  Enzymatic reaction: activation of the carboxyl group of the substrate. ❍  Chemical reaction: nucleophilic substitution reaction to be various amides.
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2013-1022-05
Life sciences
posted:2013/10/25

機能性ペプチドの合成法

KINO, Kuniki Professor (Faculty of Science and Engineering School of Advanced Science and Engineering Department of Applied Chemistry)
・非リボソーム型ペプチド合成酵素(NRPS)由来のモジュールやドメインを利用したジペプチド合成・特定アミノ酸に限定されないジペプチド合成技術
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2011-0427-03
Life sciences
posted:2014/05/21

A method of freely synthesizing hexapeptides from peptides

KINO, Kuniki Professor (Faculty of Science and Engineering School of Advanced Science and Engineering Department of Applied Chemistry)
For example, to synthesize amino acids A and B, a method of implementing biocatalysts (enzymes) enables the synthesis of specific structures only (e.g., when AA, AB, BA and BB combinations are possible, only AB may be selectively synthesized). The peptide too, gains one site-s...
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2011-0427-02
Life sciences
posted:2014/05/21

The emission of white light through enzyme hydration of 2-naphthoic acid

KINO, Kuniki Professor (Faculty of Science and Engineering School of Advanced Science and Engineering Department of Applied Chemistry)
Using cytochrome P450 (enzyme) on 2-naphthoic acid to add a hydroxyl group enables the easy, one-step synthesis of a compound that emits white light.We have also synthesized compounds that emit blue light, and there is the potential to synthesize compounds that emit a variety ...
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2011-0427-01
Life sciences
posted:2014/05/21

The synthesis of high yield hydroxyaspartic acid and its use in antitumor drugs

KINO, Kuniki Professor (Faculty of Science and Engineering School of Advanced Science and Engineering Department of Applied Chemistry)
In this research seed we succeeded in synthesizing hydroxyaspartic acid, with 100% yield, through site-specific addition of hydroxyl groups to aspartic acid in few steps, by making use of the biological reactions of enzymes.
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692
Environment Life sciences
posted:2014/04/03

Lipolytic microorganism and method for treating wastewater containing oil and fat using the same

YUI, Hiroshi Guest Professor (Faculty of Science and Engineering Waseda Research Institute for Science and Engineering) (retired)
This invention relates to a novel microorganism that can efficiently break down fats and oils from animals and vegetables that are contained in wastewater from kitchens and other sources, as well as the enzymes that are generated by this microorganism. It is a method of treati...
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