Artificial blood vessel unit for fabrication of artificial organ

2018-1123-04
researcher's name
affiliation
research field
Intelligent mechanics/Mechanical systems
keyword

background

●  For conducting drug evaluation test, three dimensional cellular tissue similar to in vivo is needed.
●  Vascular structures are required to create thick cellular tissue.
●  Creating a vascular structure with arbitral diameter inside of a tissue is difficult.

summary

●  Luminal structure was fabricated by using titanium wire and hydrogel.
●  Artificial vascular structures are created by using vascular endothelial cells adhered titanium wire.
●  Artificial vascular structures were perfused with culture medium.

predominance

●  Vascular structure of arbitral diameter can be fabricated easily without complicated method.
●  Narrow blood bessel which was difficult to create can be fabricated.
●  Culture medium can be supplied within the tissue because perfusion can be performed.

application/development

●  Drug evaluation model
●  Artificial organ, cyborg

material

collaborative researchers

SAKAGUCHI, Katsuhisa Associate Professor , 秋元 渓 , 大矢 貴史

posted: 2018/11/29