Artificial blood vessel unit for fabrication of artificial organ

researcher's name
about researcher UMEZU, Shinjiro Professor
Faculty of Science and Engineering School of Creative Science and Engineering
research field
Intelligent mechanics/Mechanical systems


●  For conducting drug evaluation test, three dimensional cellular tissue similar to in vivo is needed.
●  Vascular structures are required to create thick cellular tissue.
●  Creating a vascular structure with arbitral diameter inside of a tissue is difficult.


●  Luminal structure was fabricated by using titanium wire and hydrogel.
●  Artificial vascular structures are created by using vascular endothelial cells adhered titanium wire.
●  Artificial vascular structures were perfused with culture medium.


●  Vascular structure of arbitral diameter can be fabricated easily without complicated method.
●  Narrow blood bessel which was difficult to create can be fabricated.
●  Culture medium can be supplied within the tissue because perfusion can be performed.


●  Drug evaluation model
●  Artificial organ, cyborg


collaborative researchers

SAKAGUCHI, Katsuhisa Part-time Lecturer (Faculty of Science and Engineering Graduate School of Advanced Science and Engineering) (retired) , 秋元 渓 , 大矢 貴史

posted: 2018/11/29