表題番号：2020C-399
日付：2021/04/14
研究課題脂質代謝能力とウエスト／身長比の組み合わせから生活習慣病の罹患リスクを評価す る
| 研究者所属（当時） | 資格 | 氏名 | |
|---|---|---|---|
| （代表者） | スポーツ科学学術院 スポーツ科学部 | 教授 | 坂本 静男 |
- 研究成果概要
- PURPOSE: Obesity and decreasing fat oxidation availability are risks of lifestyle-related diseases. However, the influence of the combination of obesity and reducing fat oxidation availability is uncleared. Therefore, we conducted a cross-sectional study to investigate the relationship between the combination of obesity and decreasing fat oxidation availability and the incidence of pre-DM/DM, hypertension, and dyslipidemia among Japanese elderly people.METHODS: Participants were 1100 Japanese (723 men and 377 women) who completed a medical examination and graded exercise stress test. Maximal fat oxidation as an indicator of fat oxidation availability measured by indirect calorimetry. The study participants were divided into two groups according to the height of the waist/height ratio by gender, and then divided into two groups according to the height of the MFO and classified into four groups. Odds ratios for the prevalence of lifestyle-related diseases were obtained using logistic regression models while adjusting for age, alcohol intake, cigarette smoking, exercise habits.RESULTS: 116 men and 27 women had pre-DM/DM, 321 men and 65 women had hypertension, and 354 men and 134 women had dyslipidemia. There is no significant difference for preDM/DM both in men and women. Using high WHtR - low MFO group as a reference, the odds ratios for low WHtR – low MFO group and low WHtR – high MFO group were 0.42 and 0.34 in men and 0.31 and 0.36 in women for hypertension, and 0.45 and 0.39 in men and 0.38 and 0.44 in women for dyslipidemia, respectively.CONCLUSION: These results may suggest that the combination of obesity and reducing fat oxidation availability is associated with the prevalence of hypertension and dyslipidemia.