| 研究者所属（当時） | 資格 | 氏名 | |
|---|---|---|---|
| （代表者） | スポーツ科学学術院 スポーツ科学部 | 教授 | 坂本 静男 |
| （連携研究者） | スポーツ科学研究センター | 招聘研究員 | 小西真幸 |
| （連携研究者） | スポーツ科学学術院 | 教授 | 澤田亨 |
- 研究成果概要
PURPOSE: Maximal fat oxidation (MFO), which is the capacity to oxidize fat for energy substrates, may be associated with lifestyle-related diseases. However, limited data are available on the relationship of MFO with the prevalence of lifestyle-related diseases. We conducted a cross-sectional study to investigate the relationship between relative MFO (MFO/free fat mass) with the prevalence of hypertension, diabetes mellitus (DM), and dyslipidemia among Japanese in WASEDA'S Health Study.
METHODS: Participants were 911 Japanese who completed a medical examination and graded exercise stress test. Participants were divided into tertiles based on relative MFO. Odds ratios for the prevalence of lifestyle-related diseases were obtained using logistic regression models while adjusting for sex, age, alcohol intake, cigarette smoking, maximal oxygen uptake, physical activity, and energy intake.
RESULTS: 390 participants had hypertension, 117 had pre-DM/DM, and 443 had dyslipidemia. Using the lowest relative MFO as reference, the odds ratios for the second and third tertiles were 1.35 and 1.17, Ptrend = 0.402 for hypertension, 1.46 and 1.87, Ptrend = 0.024 for pre-DM/DM, and 1.07 and 0.93, Ptrend = 0.707 for dyslipidemia, respectively.
CONCLUSION: These results may suggest that relative MFO is associated with the prevalence of pre-DM/DM among Japanese.