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field	Life sciences Information Communication Environment Nanotechnology / Materials Energy Manufacturing Technology Social Infrastructure Frontier
title
body
researcher's name
affiliation
posted	～
type of seeds	Technology seeds IP seeds

2011-0427-01

Life sciences

posted：2014/05/21

The synthesis of high yield hydroxyaspartic acid and its use in antitumor drugs

KINO, Kuniki Professor (Faculty of Science and Engineering School of Advanced Science and Engineering Department of Applied Chemistry)

In this research seed we succeeded in synthesizing hydroxyaspartic acid, with 100% yield, through site-specific addition of hydroxyl groups to aspartic acid in few steps, by making use of the biological reactions of enzymes.

2011-0427-02

Life sciences

posted：2014/05/21

The emission of white light through enzyme hydration of 2-naphthoic acid

KINO, Kuniki Professor (Faculty of Science and Engineering School of Advanced Science and Engineering Department of Applied Chemistry)

Using cytochrome P450 (enzyme) on 2-naphthoic acid to add a hydroxyl group enables the easy, one-step synthesis of a compound that emits white light.We have also synthesized compounds that emit blue light, and there is the potential to synthesize compounds that emit a variety ...

2011-0427-03

Life sciences

posted：2014/05/21

A method of freely synthesizing hexapeptides from peptides

KINO, Kuniki Professor (Faculty of Science and Engineering School of Advanced Science and Engineering Department of Applied Chemistry)

For example, to synthesize amino acids A and B, a method of implementing biocatalysts (enzymes) enables the synthesis of specific structures only (e.g., when AA, AB, BA and BB combinations are possible, only AB may be selectively synthesized). The peptide too, gains one site-s...

2013-1022-05

Life sciences

posted：2013/10/25

機能性ペプチドの合成法

KINO, Kuniki Professor (Faculty of Science and Engineering School of Advanced Science and Engineering Department of Applied Chemistry)

・非リボソーム型ペプチド合成酵素(NRPS)由来のモジュールやドメインを利用したジペプチド合成・特定アミノ酸に限定されないジペプチド合成技術

2013-1022-06

Life sciences

posted：2013/10/25

クエン酸濃度の迅速測定法

KIRIMURA, Kotaro Professor (Faculty of Science and Engineering School of Advanced Science and Engineering Department of Applied Chemistry)

・従来法（15分程）と異なり、数秒で測定可能・有機溶媒や高価な酵素を用いず、検出感度が高い

2357

Information Communication

posted：2021/03/15

レーザービームスキャナ

KITA, Tomohiro Professor (Faculty of Science and Engineering School of Advanced Science and Engineering)

2354

Life sciences

posted：2021/01/12

光スイッチ

KITA, Tomohiro Professor (Faculty of Science and Engineering School of Advanced Science and Engineering)

2012-0625-01

Environment

posted：2014/05/21

Self-filling concrete using sea water and sea sand

KIYOMIYA, Osamu Professor (Faculty of Science and Engineering School of Creative Science and Engineering) (retired)

This project developed self-filling concrete using sea water as mixing water, sand as aggregate, and a new admixture that can provide these materials with superior fluidity and appropriate viscosity (A high-performance AE water reducing agent with a one-pack type thickener con...

2012-1019-01

Nanotechnology / Materials

posted：2014/05/21

Fabrication of Nanoparticle Phosphor Film and Solar Cell Applications

KOBAYASHI, Masakazu Professor (Faculty of Science and Engineering Waseda Research Institute for Science and Engineering)

Our laboratory made nanoparticle phosphors of several nm using the ball mill method. Transparent thin film with over 90% transmittance in all wavelength regions was fabricated using nanoparticle phosphors.Red phosphor transparent thin film that meets the following conditions i...

2230

Information Communication

posted：2021/09/06

特許第7274210号

音声対話システムにおける発話タイミング制御

KOBAYASHI, Tetsunori Professor (Faculty of Science and Engineering School of Fundamental Science and Engineering Department of Computer Science and Engineering)

システム発話タイミング検出手段は、ユーザの発話権維持又は譲渡/放棄かをパターン認識処理により逐次推定し、次発話準備手段は、システム発話タイミング検出手段と非同期、かつ開始タイミング検出前に、システムの次発話の内容データを準備する。そして、システム発話の開始タイミングの検出後に、...

2015-1023-05

Life sciences

posted：2015/10/23

Protein crystallization using membrane separation method

KOHORI, Fukashi Assistant Professor (Faculty of Science and Engineering School of Advanced Science and Engineering)

・ Protein solution is concentrated by using ultrafilter・ Concentration speed is controlled optionally by pressure control・ Separation and collection of proteins are very easy

2019-1021-03

Life sciences

posted：2019/10/21

Probes for theranostics that target denatured collagen

KOIDE, Takaki Professor (Faculty of Science and Engineering)

● Remarkable improvement of affinity to target by cyclization of CMPs● Optimization of cyclic CMP (cCMP) design using structure-activity relationship

2018-0927-02

Life sciences

posted：2018/09/27

An artificial collagen-like material based on triple helix-forming peptides

KOIDE, Takaki Professor (Faculty of Science and Engineering)

● Polymerization of the collagen-like peptides by cross-linking via disulfide bonds● Functionalization by incorporating bioactive sequences derived from native collagen● Process into a transparent membrane by a drying/rehydration of the gel

2016-1024-06

Life sciences

posted：2016/10/24

Collagen-like Peptide Polymer with Gelating Property

KOIDE, Takaki Professor (Faculty of Science and Engineering)

● Disulfide-crosslinked polymer of triple-helical peptides (Fig. 1)● The material can be shaped into hydrogels and films etc. (Fig. 2).● Cell behaviors can be regulated by introducing signaling sequences (Fig. 3).● Cell behaviors can be regulated by altering the stiffness of t...

2015-1023-03

Life sciences

posted：2015/10/23

Novel antimicrobial peptides

KOIDE, Takaki Professor (Faculty of Science and Engineering)

Novel antimicrobial peptides which form triple-helical structure and contain Arg cluster in the N-terminal region and disulfide bonds in the C-terminal region.

2011-0930-01

Life sciences

posted：2014/05/21

Drug development based on collagen

KOIDE, Takaki Professor (Faculty of Science and Engineering)

●Supramolecular materials having collagen-like triple-helical structure●Library of collagen-like triple-helical peptides (approximately 800 types)●Screening methods for collagen biological polymer bonding inhibitor compounds: (establishment of 384-well plate, high-throughput s...