Epithelial cell-cell communication to attenuate the rejection of suboptimal cells

2021-0921-03
researcher's name
about researcher MARUYAMA, Takeshi Associate Professor
affiliation
Affiliated organization Waseda Institute for Advanced Study
keyword

background

● Poor survival of  transplanted cells 
● The cells are eliminated even upon the immunosuppressant

summary

● Optimal cells eliminate suboptimal cells
● The mechanism of epithelial cell-cell  communication via the interaction between a ligand and a receptor
● MHC-I-targeting treatment suppresses the elimination

predominance

● A novel mechanism to suppress the elimination of suboptimal cells
● Low cell toxicity

application/development

● Cell transplantation
● Neurodegenerative disease

material

collaborative researchers

鮎川 志優

same researcher's seeds

  • Epithelial cell-cell communication to facilitate the aberrant cell elimination
posted: 2021/10/08