Reproduction model device for cerebral aneurysm
2018-1123-03
- researcher's name
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about researcher YAGI, Takanobu Guest Researcher
- affiliation
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Faculty of Science and Engineering Waseda Research Institute for Science and Engineering
- keyword
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background
● There is no prevention method of initiation and rupture of intracranial aneurysms.
● Animal experiments for developing drugs fail to allow us to consider the effect of hemodynamics.
● Little techniques as a drug-discovery assistance, which evaluate the effect of hemodynamics.
● Animal experiments for developing drugs fail to allow us to consider the effect of hemodynamics.
● Little techniques as a drug-discovery assistance, which evaluate the effect of hemodynamics.
summary
● Establishment of a novel ex vivo technique of reproducing cerebral aneurysm.
● Reproduce diseased state of the arteries from healthy by hemodynamic loading.
● Reproduce degenerative change of arteries due to aberrant hemodynamics.
● Reproduce diseased state of the arteries from healthy by hemodynamic loading.
● Reproduce degenerative change of arteries due to aberrant hemodynamics.
predominance
● A capability of visualizing and analyzing the progressive state of disease in a time-lapse manner.
● A capability of quantifying and controlling hemodynamics over animal experiments.
● A capability of quantifying and controlling hemodynamics over animal experiments.
application/development
● Pharmaceutical market of vascular diseases such as intracranial aneurysms.
● Its prevalence reaches 5% of the people 50 years old or older.
● No medical therapy developed, and only surgical procedures available.
● Its prevalence reaches 5% of the people 50 years old or older.
● No medical therapy developed, and only surgical procedures available.
collaborative researchers
SAKAGUCHI, Katsuhisa Part-time Lecturer (Faculty of Science and Engineering Graduate School of Advanced Science and Engineering) (retired)
posted:
2018/11/28