Regulation of Epithelial cell-cell communication to attenuate the rejection of suboptimal cell

background

● Poor survival of  transplantated cells 
● The cells are eliminated upon the immunosuppressant

summary

● Optimal cells eliminate suboptimal cells
● The mechanism similar to recognition of antigen presentation
● Inhibition of ECA1/ECAR interaction suppresses the elimination of suboptimal cells

predominance

● A novel mechanism to suppress the elimination of suboptimal cells
● Low cell toxicity

application/development

● Cell transplantation  
● Neuro degenerative disease

material

posted: 2020/10/27