Regulation of Epithelial cell-cell communication to attenuate the rejection of suboptimal cell

background

● Poor survival of transplantated cells
● The cells are eliminated upon the immunosuppressunt

summary

● Optimal cells eliminate suboptimal cells
● The mechanism similar to recognition of antigen presentaiton
● Inhibition of ECA1/ECAR interaction suppresses the elimaination of suboptimal cells

predominance

● A novel mechanism to suppress the elimination of suboptimal cells
● Low cell toxicity

application/development

● Cell transplantation

material

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posted: 2019/10/21